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What is the NMR LipoProfile test?
The NMR LipoProfile test is the first NMR based clinical application that measures and counts lipoprotein particles – container that carry cholesterol throughout the body.
The NMR LipoProfile test is used by doctors to aid in the management of cardiovascular disease (CVD) risk among individuals, including those with low or normal cholesterol levels, by quantifying the number of lipoprotein particles.
LDL-P and Heart Disease
LDL is a low density lipoprotein particle that contains varying amounts of cholesterol.
Because the amount of cholesterol within lipoprotein particles can vary between patients and even within a patient, cholesterol levels may underestimate the number of lipoprotein particles.
“… it is lipoproteins that interact with the arterial wall and set in motion the cascade of events that leads to atherosclerosis.” (Brunzell et al. JACC. 2008;15:1513-1524.)
Why use the NMR LipoProfile test?
Outcomes studies show that people with lower LDL particle numbers have fewer events than those with higher LDL particle numbers.
Lipoproteins, specifically low density lipoproteins, can be readily measured. NMR technology has recently been recognized by the American Diabetes Association and the American College of Cardiologists.
NMR LipoProfile test results can be used with clinical evaluation to aid in the diagnosis and management of lipoprotein disorders associated with cardiovascular disease.
Therapeutic lifestyle changes and pharmacologic interventions can be used to lower LDL particle number.
Who should take the NMR LipoProfile test?
There are certain factors that put people at greater risk for heart disease. A person with any of the following conditions may be a good candidate for the NMR LipoProfile test:
Previous heart attackor related event
Family history of heart attackor related event
Hypertension (high blood pressure)
Metabolic syndrome / cardiometabolic risk
Low HDL (dyslipidemia)
Anyone who wants a better understanding of their risk for heart disease should get theNMR LipoProfile test.
Fast Facts From the CDC:
Twenty-one million people in the United States 7 percent of the population have diabetes.
Despite the fact that patients with type 2 diabetes tend to have normal LDL cholesterol (LDL-C) levels, they are 3 to 5 times more likely to develop cardiovascular disease (CVD) than patients who do not have diabetes.
The primary source of this increased risk is an increased number of LDL particles (LDL-P).
Managing LDL-P to safe levels in patients with diabetes improves patient outcomes.
At least 47 million American adults are living with cardiometabolic risk/metabolic syndrome.